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Leonardo da Vinci is usually credited with conducting the first systematic study of friction in the late 15th century, a subfield now known as tribology that deals with the dynamics of interacting surfaces in relative motion. Da Vinci's notebooks depict how he pulled rows of blocks using weights and pulleys, an approach that is still used in frictional studies today, as well as examining the friction produced in screw threads, wheels, and axles. The authors of this latest paper used an experimental setup similar to da Vinci's.，详情可参考搜狗输入法2026
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Agar was first introduced into the laboratory in 1881. Since then, microbiologists have depended on agar to create strong jellies. When microorganisms are streaked or plated onto this jellied surface and incubated, individual cells multiply into distinct colonies that scientists can easily observe, select, and propagate for further experiments. Many of the most important findings in biological research of the last 150 years or so — including the discovery of the CRISPR/Cas9 gene-editing tool — have been enabled by agar.4 Agarose, a derivative of agar, is also essential in molecular biology techniques like gel electrophoresis, where its porous gel matrix separates DNA fragments by size, enabling researchers to analyze and isolate specific genetic sequences.